9-Ethyl 6-Mercaptopurine
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9-Ethyl 6-Mercaptopurine Definition
A synthetic alkyl derivative prodrug of the antineoplastic agent 6-mercaptopurine (6-MP). In vivo, 9-ethyl 6-mercaptopurine appears to be converted to 6-MP, which substitutes for the normal nucleoside and fraudulently incorporates into DNA and inhibits de novo purine synthesis, thereby inducing cell death. (NCI04)
9-Ethyl 6-Mercaptopurine Synonyms
9-Ethyl 6-Mercaptopurine, 9-Ethyl 6-MP
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