A Kinase Anchor Protein-9

Cancer Terms -> Gene Product -> Protein -> Protein Organized by Function -> Signaling Protein -> A Kinase Anchor Protein-9

A Kinase Anchor Protein-9 Definition

Encoded by human AKAP9 Gene, 3911-amino acid 454 kD A Kinase Anchor Protein 9 is widely expressed as alternative isoforms: 1, 2, 3/CG-NAP, 4/Yotiao, 5, and 6/AKAP350. Full-length protein contains many coiled-coil regions. Centrosomal, cytoskeletal, cytoplasmic, or associated with postsynaptic densities, AKAP9 appears to be a scaffolding protein for protein kinases and phosphatases. AKAP9 interacts with the regulatory region of PKN, PP2A, PP1 and PKC Epsilon. Highly expressed in the pancreas and at synapses, isoform 4/Yotiao interacts with a NMDA receptor NR1 subunit alternatively spliced intracellular C-terminus and may modulate synaptic transmission. Yotiao binds to PP1 and PKA RII, indicating that it is an AKAP. (OMIM, Swiss-Prot, and NCI)

A Kinase Anchor Protein-9 Synonyms

A Kinase Anchor Protein 9, A Kinase (PRKA) Anchor Protein (Yotiao) 9, A-Kinase Anchor Protein 350 kD, A-Kinase Anchor Protein 450 kD, AKAP 120 Like Protein, AKAP 350, AKAP 450, AKAP9, CG-NAP, Centrosome- and Golgi-Localized PKN-Associated Protein, Hyperion, PRKA9, Protein Kinase A Anchoring Protein 9, Yotiao

A Kinase Anchor Protein-9

A Kinase Anchor Protein-9 Definition

A Kinase Anchor Protein-9 Synonyms

Terms in A Kinase Anchor Protein-9 category