ABCB1 wt Allele

Cancer Terms -> Gene -> Ligand Binding Protein Gene -> Transport Protein Gene -> ABCB1 Gene -> ABCB1 wt Allele

ABCB1 wt Allele Definition

Human ABCB1 wild-type allele is located in the vicinity of 7q21.1 and is approximately 210 kb in length. This allele, which encodes multidrug resistance protein 1, is involved in transmembrane transport. Amplification of the ABCB1 gene is a major determinant in the development of multi-drug resistance, which decreases the effectiveness of many chemotherapeutic agents used in cancer treatment.

ABCB1 wt Allele Synonyms

ABCB1 wt Allele, ABC20, ABCB1, ABCB1 1 Allele, ABCB1-C, ABCB1-C Allele, ATP-Binding Cassette, Sub-Family B (MDR/TAP), Member 1 wt Allele, GP170, MDR-1, MDR1, MDR1 Gene, MDR1-C, MDR1-C Allele, Multidrug Resistance 1 Gene, P-GP, P-Glycoprotein 1 Gene, P-Glycoprotein Transporter C Allele, PGY1

Terms in ABCB1 wt Allele category

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