Cancer Terms

ABL2 Tyrosine Kinase

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ABL2 Tyrosine Kinase Definition

ABL2 tyrosine kinase is related to ABL. A case of acute myeloid leukemia M4 carrying the t(1;12)(q25;p13) translocation involves a fusion between ETV6 and ABL2, resulting in a chimeric protein consisting of the HLH oligomerization domain of ETV6 and the SH2, SH3, and protein tyrosine kinase domains of ABL2. (from OMIM 164690 and NCI)

ABL2 Tyrosine Kinase Synonyms

ABL2 Tyrosine Kinase, ABL2, ABL2 Tyrosine-Protein Kinase, ARG Tyrosine Kinase

Terms in ABL2 Tyrosine Kinase category



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