AEE788
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Tyrosine Kinase Inhibitor -> AEE788
AEE788 Definition
An orally bioavailable multiple-receptor tyrosine kinase inhibitor. AEE788 inhibits phosphorylation of the tyrosine kinases of epidermal growth factor receptor (EGFR), human epidermal growth factor receptor 2 (HER2), and vascular endothelial growth factor receptor 2 (VEGF2), resulting in receptor inhibition, the inhibition of cellular proliferation, and induction of tumor cell and tumor-associated endothelial cell apoptosis. (NCI05)
AEE788 Synonyms
AEE788, AEE 788, AEE-788
Terms in AEE788 category
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