APC wt Allele

Cancer Terms -> Gene -> Signaling Pathway Gene -> APC Gene -> APC wt Allele

APC wt Allele Definition

Human APC wild-type allele is located within 5q21-q22 and is approximately 108 kb in length. This allele, which encodes adenomatosis polyposis coli protein, is involved in the progression of Wnt protein mediated signaling. Mutations in this gene are associated with familial adenomatous polyposis, an autosomal dominant pre-malignant disease that usually progresses to malignancy.

APC wt Allele Synonyms

APC wt Allele, Adenomatosis Polyposis Coli wt Allele, DP2, DP2.5, DP3, FAP, FPC, GS

Terms in APC wt Allele category

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