APP wt Allele
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APP wt Allele Definition
Human APP wild-type allele is located in the vicinity of 22q13.2 and is approximately 290 kb in length. This allele, which encodes amyloid beta A4 protein, is involved in transcriptional activation and peptide regulation. APP defects can cause Alzheimer's disease and cerebroarterial amyloidosis.
APP wt Allele Synonyms
APP wt Allele, A4, AAA, ABETA, AD1, Amyloid Beta (A4) Precursor Protein (Protease Nexin-II, Alzheimer Disease) wt Allele, CVAP
Terms in APP wt Allele category
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