APRIN Protein

Cancer Terms -> Gene Product -> Protein -> Protein Organized by Function -> Regulatory Protein -> Cell Cycle Protein -> APRIN Protein

APRIN Protein Definition

Encoded by human AS3 Gene, 1391-amino acid 158 kD AS3 Protein appears to be an androgen-induced tumor suppressor that mediates G0/G1 cell cycle arrest (androgen-induced proliferative shutoff). AS3 protein has putative transactivating features, protein-protein interaction motifs (coiled-coil and leucine zipper), and DNA-binding domains, suggesting that AS3 is a transcription factor. AS3 also has a protein-kinase motif, suggesting that it may phosphorylate a target protein. (Swiss-Prot, OMIM, and NCI)

APRIN Protein Synonyms

Androgen-Induced Prostate Proliferative Shutoff Associated Protein, APRIN

Terms in APRIN Protein category

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