ATR wt Allele

Cancer Terms -> Gene -> DNA Repair Gene -> ATR Gene -> ATR wt Allele

ATR wt Allele Definition

Human ATR wild-type allele is located within 3q22-q24 and is approximately 130 kb in length. This allele, which encodes serine/threonine-protein kinase ATR protein, plays an essential role in cell cycle checkpoints required for cell cycle arrest and DNA damage repair in response to DNA damage. This allele may be particularly essential in the early embryo to sense incomplete DNA replication and prevent mitotic catastrophe.

ATR wt Allele Synonyms

ATR wt Allele, Ataxia-Telangiectasia and Rad3-Related wt Allele, FRP1

Terms in ATR wt Allele category

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