Alitretinoin
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Retinoic Acid Agent -> Alitretinoin
Alitretinoin Definition
An orally- and topically-active naturally-occurring retinoic acid with antineoplastic, chemopreventive, teratogenic, and embryotoxic activities. Alitretinoin binds to and activates nuclear retinoic acid receptors (RAR) and retinoid X receptors (RXR); these activated receptors act as transcription factors, regulating gene expression that results in the inhibition of cell proliferation, induction of cell differentiation, and apoptosis of both normal cells and tumor cells.
Alitretinoin Synonyms
Alitretinoin, 3,7-Dimethyl-9-(2,6,6-trimethyl-1-cyclohexen-1-yl)2-trans-4-trans-6-cis-8-trans-nonatetraenoic Acid, 9-Cis-Retinoic Acid, 9-cRA, 9-cis Retinoic Acid, 9-cis retinoic acid, 9-cis-RA, 9-cis-Retinoic Acid, ALITRETINOIN, ALRT1057, LGD1057, Panretin, Panretyn, Panrexin, Retinoicacid-9-cis
Terms in Alitretinoin category
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