Cancer Terms

Alitretinoin

Cancer Terms -> Drugs and Chemicals -> Pharmacologic Substance -> Antineoplastic Agent -> Cell Differentiating Agent -> Differentiation Inducer -> Retinoic Acid Agent -> Alitretinoin

Alitretinoin Definition

An orally- and topically-active naturally-occurring retinoic acid with antineoplastic, chemopreventive, teratogenic, and embryotoxic activities. Alitretinoin binds to and activates nuclear retinoic acid receptors (RAR) and retinoid X receptors (RXR); these activated receptors act as transcription factors, regulating gene expression that results in the inhibition of cell proliferation, induction of cell differentiation, and apoptosis of both normal cells and tumor cells.

Alitretinoin Synonyms

Alitretinoin, 3,7-Dimethyl-9-(2,6,6-trimethyl-1-cyclohexen-1-yl)2-trans-4-trans-6-cis-8-trans-nonatetraenoic Acid, 9-Cis-Retinoic Acid, 9-cRA, 9-cis Retinoic Acid, 9-cis retinoic acid, 9-cis-RA, 9-cis-Retinoic Acid, ALITRETINOIN, ALRT1057, LGD1057, Panretin, Panretyn, Panrexin, Retinoicacid-9-cis

Terms in Alitretinoin category



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