Altretamine

Cancer Terms -> Drugs and Chemicals -> Pharmacologic Substance -> Antineoplastic Agent -> Alkylating Agent -> Antineoplastic Alkylating Agent -> Ethylenimine Compound -> Altretamine

Altretamine Definition

A synthetic cytotoxic s-triazine derivative similar in structure to alkylating agent triethylenemelamin with antineoplastic activity. Although the precise mechanism by which altretamine exerts its cytotoxic effect is unknown, N-demethylation of altretamine may produce reactive intermediates which covalently bind to DNA, resulting in DNA damage. (NCI04)

Altretamine Synonyms

Altretamine, 2,4,6-Tris(dimethylamino)-s-triazine, 2,4,6-tris(dimethylamino)-s-triazine, ALTRETAMINE, ENT 50852, ENT-50852, HMM, HXM, Hemel, Hexalen, Hexaloids, Hexamethylmelamine, Hexastat, Hexinawas, N,N,N',N',N",N"-hexamethyl-1,3,5-triazine-2,4,6-triamine, N,n,n',N"N"-hexamethyl-1,3,5,-triazine-2,4,6,-triamine, RB-1515, WR-95704, altretamine, s-Triazine, 2,4,6-tris(dimethylamino)-

Terms in Altretamine category

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