Alvocidib Freebase
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Alvocidib Freebase Definition
The free base form of a synthetic N-methylpiperidinyl chlorophenyl flavone compound. As an inhibitor of cyclin-dependent kinase, alvocidib induces cell cycle arrest by preventing phosphorylation of cyclin-dependent kinases (CDKs) and by down-regulating cyclin D1 and D3 expression, resulting in G1 cell cycle arrest and apoptosis. This agent is also a competitive inhibitor of adenosine triphosphate activity.
Alvocidib Freebase Synonyms
Alvocidib Freebase, -)cis-5,7-Dihydroxy-2-(2-chlorophenyl)-8-(4-(3-hydroxy-1-methyl)piperidinyl)-4H-1-benzopyran-4-one, ALVOCIDIB FREEBASE, Flavopiridol, L-868275, flavopiridol
Terms in Alvocidib Freebase category
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