Cancer Terms

Anagrelide Hydrochloride

Cancer Terms -> Drugs and Chemicals -> Pharmacologic Substance -> Agent Affecting Blood And Body Fluid -> Antiplatelet Agent -> Anagrelide Hydrochloride

Anagrelide Hydrochloride Definition

The hydrochloride salt of a synthetic quinazoline derivative, Anagrelide Hydrochloride reduces platelet production through a decrease in megakaryocyte maturation. Anagrelide inhibits cyclic AMP phosphodiesterase, as well as ADP- and collagen-induced platelet aggregation. At therapeutic doses, it does not influence white cell counts or coagulation parameters. Anagrelide is used for treatment of essential thrombocythemia to reduce elevated platelet counts and the risk of thrombosis. (NCI04)

Anagrelide Hydrochloride Synonyms

Anagrelide Hydrochloride, ANAGRELIDE HYDROCHLORIDE, Agrylin

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