Cancer Terms

Angiotensin II Receptor Antagonist

Cancer Terms -> Drugs and Chemicals -> Pharmacologic Substance -> Agent Affecting Cardiovascular System -> Antihypertensive Agent -> Angiotensin II Receptor Antagonist

Angiotensin II Receptor Antagonist Definition

A class of agents that act by selectively inhibiting angiotensin II receptor activation in the renin-angiotensin-aldosterone system. Angiotensin II receptor antagonists bind to and block the activation of angiotensin II type 1 (AT1) receptors, thereby reducing production and secretion of aldosterone, amongst other actions. The combined effects result in reduction of blood pressure. Although this class of agents is also used in diabetic nephropathy (kidney damage due to diabetes) and congestive heart failure, it is primarily used for the treatment of hypertension in cases where the patient is intolerant of ACE inhibitor therapy.

Angiotensin II Receptor Antagonist Synonyms

Angiotensin II Receptor Antagonist, ARB, Angiotensin II Receptor Antagonists, Angiotensin II Receptor Blocker, Angiotensin Receptor Blockers

Terms in Angiotensin II Receptor Antagonist category

Abitesartan
Azilsartan
Azilsartan Kamedoxomil
Azilsartan Medoxomil
Candesartan
Candesartan Cilexetil
Elisartan
Eprosartan
Eprosartan Mesylate
Fimasartan
Forasartan
Irbesartan
Losartan
Losartan Hydrochlorothiazide
Losartan Potassium
Milfasartan
Olmesartan
Olmesartan Medoxomil
Pomisartan
Pratosartan
Telmisartan
Valsartan
Zolasartan



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