Anti-Cytotoxic T-Lymphocyte-Associated Antigen-4 Monoclonal Antibody
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Anti-Cytotoxic T-Lymphocyte-Associated Antigen-4 Monoclonal Antibody Definition
A monoclonal antibody directed against cytotoxic T-lymphocyte-associated antigen-4 (CTLA4), an antigen that is expressed on activated T-cells and exhibits affinity for B7 co-stimulatory molecules. By binding CTLA4, ipilimumab enhances T-cell activation and blocks B7-1 and B7-2 T-cell co-stimulatory pathways.
Anti-Cytotoxic T-Lymphocyte-Associated Antigen-4 Monoclonal Antibody Synonyms
Ipilimumab, Anti-Cytotoxic T-Lymphocyte-Associated Antigen-4 Monoclonal Antibody, IPILIMUMAB, MDX-010, MDX-CTLA4
Terms in Anti-Cytotoxic T-Lymphocyte-Associated Antigen-4 Monoclonal Antibody category
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