Anti-Endoglin Chimeric Monoclonal Antibody TRC105
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Anti-Endoglin Chimeric Monoclonal Antibody TRC105 Definition
A human/murine chimeric monoclonal antibody directed against endoglin (CD105) with potential antiangiogenic and antineoplastic activities. Anti-endoglin monoclonal antibody TRC105 binds to endoglin, which may result in inhibition of tumor angiogenesis and decreased tumor cell proliferation. The glycoprotein endoglin is a transforming growth factor beta-1 (TGF beta-1) accessory receptor that is highly expressed on tumor vessel endothelial cells and appears to be essential for angiogenesis.
Anti-Endoglin Chimeric Monoclonal Antibody TRC105 Synonyms
Anti-Endoglin Chimeric Monoclonal Antibody TRC105, TRC105
Terms in Anti-Endoglin Chimeric Monoclonal Antibody TRC105 category
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