Anti-KIR Monoclonal Antibody 1-7F9
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Anti-KIR Monoclonal Antibody 1-7F9 Definition
A human monoclonal antibody directed against the human inhibitory killer IgG-like receptor (KIR) with potential immunostimulating and antineoplastic activities. Anti-KIR monoclonal antibody 1-7F9 binds to the KIR receptor expressed on human natural killer (NK) cells, which may prevent KIR-mediated inhibition of NK cells and permit NK cell-mediated anti-tumor cytotoxicity. KIRs are surface glycoproteins that bind to major histocompatibility complex (MHC)/human leukocyte antigen (HLA) class I subtypes on target cells; binding of KIRs inhibits NK cell-mediated cytotoxicity.
Anti-KIR Monoclonal Antibody 1-7F9 Synonyms
Anti-KIR Monoclonal Antibody 1-7F9, 1-7F9
Terms in Anti-KIR Monoclonal Antibody 1-7F9 category
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