Anti-Mullerian Hormone Receptor Type-II

Cancer Terms -> Gene Product -> Protein -> Protein Organized by Function -> Ligand Binding Protein -> Receptor -> Cell Surface Receptor -> Receptor Serine-Threonine Kinase -> Anti-Mullerian Hormone Receptor Type-II

Anti-Mullerian Hormone Receptor Type-II Definition

Encoded by human AMHR2 Gene, the 573-amino acid 62.7 kD Anti-Mullerian Hormone Receptor Type II Ser/Thr protein kinase (TGFB Receptor Family) is a type I membrane protein. Type II receptors bind ligand but require a type I receptor for signal transduction. Anti-Mullerian Hormone (AMH/MIS/MIF), produced by Sertoli cells, induces regression of Mullerian ducts, which differentiate into the uterus and fallopian tubes. Type I persistent Mullerian duct syndrome is caused by AMH gene mutation; type II syndrome is due to AMHR mutation. (OMIM, Swiss-Prot, and NCI)

Anti-Mullerian Hormone Receptor Type-II Synonyms

Anti-Mullerian Hormone Receptor Type II, AMH Type II Receptor, AMHR, AMHR2, Anti-Mullerian Hormone Receptor, Anti-Mullerian Hormone Type II Receptor, MIS Type II Receptor, MISRII, MRII

Terms in Anti-Mullerian Hormone Receptor Type-II category

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