Antineoplaston Agent

Cancer Terms -> Drugs and Chemicals -> Pharmacologic Substance -> Antineoplastic Agent -> Cell Differentiating Agent -> Differentiation Inducer -> Antineoplaston Agent

Antineoplaston Agent Definition

A class of peptides, amino acid derivatives, and/or organic acids extracted from blood serum, urine, or synthesized chemically. Antineoplastons inhibit the methylation of nucleic acids and the incorporation of L-glutamine into tumor-cell proteins. These agents also intercalate into DNA, leading to cell cycle arrest in the G1 phase and inhibition of mitosis and terminal cell differentiation. In addition, antineoplastons may inhibit RAS oncogene expression and activate the tumor suppressor gene p53, resulting in cell differentiation and apoptosis. (NCI04)

Antineoplaston Agent Synonyms

Antineoplaston Agent, Antineoplastons, antineoplastons

Terms in Antineoplaston Agent category

Antineoplaston A10
Antineoplaston AS2-1