Apolizumab
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Apolizumab Definition
A humanized monoclonal antibody directed against 1D10, a polymorphic determinant on the HLA-DR beta chain that is expressed on normal and neoplastic B cells. Apolizumab induces complement-mediated cytotoxicity, antibody-dependent cell-mediated cytotoxicity, and apoptosis of 1D10 antigen-positive B cells in vitro. (NCI04)
Apolizumab Synonyms
Apolizumab, 1D1O Anti-lymphoma Antibody, MoAb Hu1D10, MoAb: Hu1D10, Monoclonal Antibody Hu1D10, Monoclonal antibody 1D10, Remitogen, apolizumab
Terms in Apolizumab category
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