Cancer Terms

Arachidonate 15-Lipoxygenase

Cancer Terms -> Gene Product -> Protein -> Protein Organized by Function -> Enzyme -> Oxidoreductase -> Oxygenase -> Arachidonate 15-Lipoxygenase

Arachidonate 15-Lipoxygenase Definition

Encoded by human ALOX15 Gene, a putative mutator gene regulated by tumor-suppressor TP53, 661-amino acid 74.7 kD cytoplasmic Arachidonate 15-Lipoxygenase (Lipoxygenase Family) acts in leukotriene biosynthesis and is implicated in anti-inflammation, membrane remodeling, and cancer development or metastasis. It converts arachidonic acid to 15s-hydroperoxyeicosatetraenoic acid. (OMIM, Swiss-Prot, and NCI)

Arachidonate 15-Lipoxygenase Synonyms

Arachidonate 15-Lipoxygenase, 15-LOX, 15-Lipoxygenase, Reticulocyte Arachidonate, ALOX15, Arachidonate Omega-6 Lipoxygenase

Terms in Arachidonate 15-Lipoxygenase category



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