Aurora Kinase Inhibitor AMG 900
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Aurora Kinase Inhibitor AMG 900 Definition
A small-molecule inhibitor of Aurora kinases A, B and C with potential antineoplastic activity. Aurora kinase inhibitor AMG 900 selectively binds to and inhibits the activities of Aurora kinases A, B and C, which may result in inhibition of cellular division and proliferation in tumor cells that overexpress these kinases. Aurora kinases are serine-threonine kinases that play essential roles in mitotic checkpoint control during mitosis and are overexpressed by a wide variety of cancer cell types.
Aurora Kinase Inhibitor AMG 900 Synonyms
Aurora Kinase Inhibitor AMG 900, AMG 900
Terms in Aurora Kinase Inhibitor AMG 900 category
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