Autologous Dendritic Cells
Cancer Terms -> Drugs and Chemicals -> Pharmacologic Substance -> Biological Agent -> Autologous Lymphocytes -> Autologous Dendritic Cells
Autologous Dendritic Cells Definition
A population of a type of antigen-presenting cell (APC), the dendritic cell (DC), harvested from a patient and grown in vitro in the presence of tumor-associated antigens (TAAs) derived from the patient's tumor (a technique known as 'pulsing') and then injected back into the patient; autologous DCs so manipulated may stimulate a specific cell-mediated antitumoral cytotoxicity. DCs derived from a patient may also be fused with the patient's tumor cells in vitro to combine sustained tumor antigen expression with the antigen-presenting and immunostimulatory capacities of DCs; when injected back into the patient, these autologous DC-tumor cell hybrids (fusion cells) may stimulate an active antitumoral immune response.Autologous Dendritic Cells Synonyms
Therapeutic Autologous Dendritic CellsTerms in Autologous Dendritic Cells category
Ad5F35-LMP1 LMP2-Transduced Autologous Dendritic CellsCEA RNA-pulsed Autologous Human Cultured Dendritic Cells