Cancer Terms

Azotomycin

Cancer Terms -> Drugs and Chemicals -> Pharmacologic Substance -> Antineoplastic Agent -> Antineoplastic Antibiotic -> Miscellaneous Antineoplastic Antibiotic -> Azotomycin

Azotomycin Definition

An antineoplastic-antibiotic diazo analog of L-glutamine isolated from the bacterium Streptomyces ambofaciens. Azotomycin inhibits glutamine-dependent enzymes involved in purine and pyrimidine biosynthesis, resulting in inhibition of DNA synthesis. (NCI04)

Azotomycin Synonyms

Azotomycin, A 10270B, Diazomycin B, Duazomycin B, L-Norleucine, 6-diazo-N-(6-diazo-N-L-.gamma.-glutamyl-5-oxo-L-norleucyl)-5-oxo- (8CI 9CI)

Terms in Azotomycin category



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