Cancer Terms

B-Cell Activation

Cancer Terms -> Biological Process -> Multicellular Process -> Host Defense Mechanism -> Immune Function -> Immune Cell Activation -> Lymphocyte Activation -> B-Cell Activation

B-Cell Activation Definition

A set of events occurring in B lymphocytes following stimulation with cognate antigen. Crosslinking the B cell antigen receptor (surface immunoglobulin) leads to increased expression of MHC class II molecules, exit from the resting state (G0) into the G1 phase of the cell cycle, and in the case of a strong antigenic stimulus, proliferation.

B-Cell Activation Synonyms

B-Cell Activation

Terms in B-Cell Activation category



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