B-Cell Survival Pathway

Cancer Terms -> Biochemical Pathway -> Regulatory Pathways -> Immune Response Regulation Pathway -> B-Cell Survival Pathway

B-Cell Survival Pathway Definition

Physical interactions between integrin alpha4beta1 heterodimer expressed on B cells and counter receptors on stroma cells are key mediators of the survival of normal and malignant B cells. Recent data indicate that integrin stimulation increases FBI-1, XIAP, survivin, and CCT4 expression but inhibits Requiem, c-Fos, and caspase 3 and 7 induction. (Biocarta)

B-Cell Survival Pathway Synonyms

B-Cell Survival Pathway, B Cell Survival Pathway

Terms in B-Cell Survival Pathway category

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