BI 2536
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Mitotic Enzyme Modulator -> BI 2536
BI 2536 Definition
A small molecule compound with potential antineoplastic activities. BI 2536 binds to and inhibits Polo-like kinase 1 (Plk1), resulting in mitotic arrest, disruption of cytokinesis, and apoptosis in susceptible tumor cell populations. Plk1, a serine/threonine-protein kinase, is a key regulator of multiple processes fundamental to mitosis and cell division.
BI 2536 Synonyms
BI 2536
Terms in BI 2536 category
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