BIBX 1382
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Epidermal Growth Factor Receptor Tyrosine Kinase Inhibitor -> BIBX 1382
BIBX 1382 Definition
A pyrimido-pyrimidine with antitumor activity. BIBX 1382 inhibits the intracellular tyrosine kinase domain of the Epidermal Growth Factor Receptor (EGFR) thus specifically reversing the aberrant enzymatic activity from overexpressed and constitutively activated EGFR, and subsequently inhibiting cell proliferation and inducing cell differentiation.
BIBX 1382 Synonyms
BIBX 1382, BIBX1382
Terms in BIBX 1382 category
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