BMS-275291
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Matrix Metalloproteinase Inhibitor -> BMS-275291
BMS-275291 Definition
A sulfhydryl-based second-generation matrix metalloproteinase (MMP) inhibitor with potential antineoplastic activity. Rebimastat selectively inhibits several MMPs (MMP 1, 2, 8, 9, and 14), thereby inducing extracellular matrix degradation, and inhibiting angiogenesis, tumor growth and invasion, and metastasis.
BMS-275291 Synonyms
Rebimastat, BMS-275291, D2163, N-((2S)-2-Mercapto-1-oxo-4-(3,4,4-trimethyl-2,5-dioxo-1-imidazolidinyl)butyl)-L-leucyl-N,3-dimethyl-L-valinamide, REBIMASTAT
Terms in BMS-275291 category
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