BRAF Inhibitor GSK2118436
Cancer Terms ->
Drugs and Chemicals ->
Pharmacologic Substance ->
Enzyme Inhibitor ->
Protein Kinase Inhibitor ->
Serine Threonine Kinase Inhibitor -> BRAF Inhibitor GSK2118436
BRAF Inhibitor GSK2118436 Definition
An orally bioavailable inhibitor of B-raf (BRAF) protein with potential antineoplastic activity. BRAF inhibitor GSK2118436 selectively binds to and inhibits the activity of B-raf, which may inhibit the proliferation of tumor cells which contain a mutated BRAF gene. B-raf belongs to the raf/mil family of serine/threonine protein kinases and plays a role in regulating the MAP kinase/ERKs signaling pathway, which may be constitutively activated due to BRAF gene mutations.
BRAF Inhibitor GSK2118436 Synonyms
BRAF Inhibitor GSK2118436, GSK2118436
Terms in BRAF Inhibitor GSK2118436 category
Copyright © Cancer Terms 2014 All rights reserved. | Terms of Use | Low Carb Foods
No reproduction or republication permitted.