Cancer Terms

BRAF Inhibitor GSK2118436

Cancer Terms -> Drugs and Chemicals -> Pharmacologic Substance -> Enzyme Inhibitor -> Protein Kinase Inhibitor -> Serine Threonine Kinase Inhibitor -> BRAF Inhibitor GSK2118436

BRAF Inhibitor GSK2118436 Definition

An orally bioavailable inhibitor of B-raf (BRAF) protein with potential antineoplastic activity. BRAF inhibitor GSK2118436 selectively binds to and inhibits the activity of B-raf, which may inhibit the proliferation of tumor cells which contain a mutated BRAF gene. B-raf belongs to the raf/mil family of serine/threonine protein kinases and plays a role in regulating the MAP kinase/ERKs signaling pathway, which may be constitutively activated due to BRAF gene mutations.

BRAF Inhibitor GSK2118436 Synonyms

BRAF Inhibitor GSK2118436, GSK2118436

Terms in BRAF Inhibitor GSK2118436 category



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