BUB1 wt Allele

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BUB1 wt Allele Definition

Human BUB1 wild-type allele is located in the vicinity of 2q14 and is approximately 40 kb in length. This allele, which encodes mitotic checkpoint serine/threonine-protein kinase BUB1 protein, is involved in the regulation of spindle checkpoints and mitotic integrity. Mutations in this gene, which generate allelic variants have been associated with aneuploidy and several forms of cancer.

BUB1 wt Allele Synonyms

BUB1 wt Allele, BUB1 Budding Uninhibited by Benzimidazoles 1 Homolog wt Allele, BUBR1 Gene, MAD3L Gene, hBUB1 Gene

Terms in BUB1 wt Allele category

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