Bcl-2 Homology Domain

Cancer Terms -> Anatomic Structure System or Substance -> Microanatomy -> Macromolecular Structure -> Protein Structure -> Protein Domain -> Ligand Binding Domain -> Protein Binding Domain -> Bcl-2 Homology Domain

Bcl-2 Homology Domain Definition

Proteins that are related to bcl-2 are characterized by the presence of one or more highly conserved stretches of homology with bcl-2, designated BH1, BH2, BH3, BH4. These domains control the ability of these proteins to homo- and heterodimerize with other proteins. Competitive dimerization between family members is thought to regulate their function as regulators of apoptosis.

Bcl-2 Homology Domain Synonyms

Terms in Bcl-2 Homology Domain category

BH1 Domain
BH2 Domain
BH3 Domain
BH4 Domain