Cancer Terms

Bemiparin Sodium

Cancer Terms -> Drugs and Chemicals -> Pharmacologic Substance -> Agent Affecting Blood And Body Fluid -> Anticoagulant Agent -> Low Molecular Weight Heparin -> Bemiparin Sodium

Bemiparin Sodium Definition

The sodium salt of bemiparin, a second generation, synthetic, low-molecular-weight heparin (LMWH) with anticoagulant activity. Derived, after depolymerisation and fractionation, from medical-grade porcine unfractionated heparin (UFH), bemiparin has an average molecular weight of 3,600 daltons and has a higher anti-factor Xa/anti-factor IIa ratio (8:1) than first-generation LMWHs. This anticoagulant binds to antithrombin III, thereby enhancing the inactivation of activated factor X (Factor Xa) and, to a lesser extent, activated factor II (Factor IIa). Compared to unfractionated heparins, the use of bemiparin is associated with lower incidences of major bleeding, osteoporosis, and heparin-induced thrombocytopenia. Bemiparin also promotes a greater release of tissue factor pathway inhibitor than UFH or dalteparin.

Bemiparin Sodium Synonyms

Bemiparin Sodium, Badyket, Hibor, Ivor, Zibor

Terms in Bemiparin Sodium category



Copyright © Cancer Terms 2014 All rights reserved. | Terms of Use | Low Carb Foods

No reproduction or republication permitted.