Beta Adrenergic Receptor

Cancer Terms -> Gene Product -> Protein -> Protein Organized by Function -> Ligand Binding Protein -> Receptor -> Cell Surface Receptor -> G Protein-Coupled Receptor -> Beta Adrenergic Receptor

Beta Adrenergic Receptor Definition

Expressed by Beta Adrenergic Receptor Genes in effector tissues innervated by postganglionic sympathetic adrenergic fibers, Beta Adrenergic Receptors are one of two major classes of adrenergic receptors (alpha and beta) based on their reactions to norepinephrine and epinephrine, on cellular effects of receptor activation, and on relative affinities and reactions to synthetic blocking or stimulating agents. Beta-adrenergic receptors respond to blocking agents such as propranolol and to activating agents such as isoproterenol. Beta-1 type receptors mediate lipolysis and increase cardiac rate and force of contraction; beta-2 type receptor activation promotes bronchial and vascular smooth muscle relaxation. When coupled to adenylate cyclase through Gs protein, Beta Adrenergic Receptor stimulation results in increased intracellular cyclic AMP. (NCI)

Beta Adrenergic Receptor Synonyms

Terms in Beta Adrenergic Receptor category

Beta-1 Adrenergic Receptor
Beta-2 Adrenergic Receptor