Beta Adrenergic Receptor Gene

Cancer Terms -> Gene -> Ligand Binding Protein Gene -> Receptor Gene -> G Protein-Coupled Receptor Gene -> Beta Adrenergic Receptor Gene

Beta Adrenergic Receptor Gene Definition

Expressed in effector tissues innervated by postganglionic sympathetic adrenergic fibers, Beta Adrenergic Receptor Genes encode Beta Adrenergic Receptors, one of two major classes of adrenergic receptors (alpha and beta) based on their reactions to norepinephrine and epinephrine, on cellular effects of receptor activation, and on relative affinities and reactions to synthetic blocking or stimulating agents. Beta-adrenergic receptors respond to blocking agents such as propranolol and to activating agents such as isoproterenol. Beta-1 type receptors mediate lipolysis and increase cardiac rate and force of contraction; beta-2 type receptor activation promotes bronchial and vascular smooth muscle relaxation. When coupled to adenylate cyclase through Gs protein, Beta Adrenergic Receptor stimulation results in increased intracellular cyclic AMP. (NCI)

Beta Adrenergic Receptor Gene Synonyms

Terms in Beta Adrenergic Receptor Gene category

ADRB1 Gene
ADRB2 Gene