Beta-Thioguanine Deoxyriboside
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Beta-Thioguanine Deoxyriboside Definition
A thiopurine nucleoside derivative with antineoplastic activity. After conversion to the triphosphate, beta-thioguanine deoxyriboside is incorporated into DNA, resulting in inhibition of DNA replication. This agent is cytotoxic against leukemia cell lines and has demonstrated some activity against leukemia cells in vivo. Beta-thioguanine deoxyriboside demonstrates antineoplastic activity against 6-thioguanine-resistant tumor cells. (NCI04)
Beta-Thioguanine Deoxyriboside Synonyms
Beta-Thioguanine Deoxyriboside, .beta.-2'-Deoxy-6-thioguanosine, .beta.-2'-Deoxythioguanosine, .beta.-2'-Deoxythiol guanosine, .beta.-Thioguanine deoxyriboside, 1,9-dihydro-6H-purine-6-thione, 2-amino-9-(2-deoxy-beta-D-erythro-pentofuranosyl), 2'-Deoxythioguanosine, 2'-Desoxy-6-thioguanosine, 2'-deoxythioguanosine, 2'-desoxy-6-thioguanosine, 6-Mercaptoguaninedeoxyriboside, 6H-Purine-6-thione, 2-amino-9-(2-deoxy-.beta.-D-erythro-pentofuranosyl)-1,9-dihydro-, 9H-Purine-6-thiol, 2-amino-9-(2-deoxy-.beta.-D-erythro-pentofuranosyl)-, monohydrate, 9H-purine-6-thiol, 2-amino-9-(2-deoxy-beta-D-erythro-pentofuranosyl) monohydrate, B-TGDR, BTG, Beta Thioguanine Deoxyriboside, Thioguanine 9.beta.D-2'-deoxyriboside, beta-2'-deoxy-6-thioguanosine, beta-2'-deoxythioguanosine, beta-2'-deoxythiol guanosine, thioguanine 9-.beta-D-2'-deoxyriboside
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