Cancer Terms

Bexarotene

Cancer Terms -> Drugs and Chemicals -> Pharmacologic Substance -> Antineoplastic Agent -> Cell Differentiating Agent -> Differentiation Inducer -> Retinoic Acid Agent -> Bexarotene

Bexarotene Definition

A synthetic retinoic acid agent with potential antineoplastic, chemopreventive, teratogenic and embryotoxic properties. Bexarotene selectively binds to and activates retinoid X receptors (RXRs), thereby inducing changes in gene expression that lead to cell differentiation, decreased cell proliferation, apoptosis of some cancer cell types, and tumor regression. (NCI04)

Bexarotene Synonyms

Bexarotene, 3-methyl TTNEB, 4-[1-(5,6,7,8-Tetrahydro-3,5,5,8,8-pentamethyl-2-naphthalenyl)ethenyl]benzoic Acid, BEXAROTENE, LGD1069, Targretin, bexarotene

Terms in Bexarotene category



Copyright © Cancer Terms 2014 All rights reserved. | Terms of Use | Low Carb Foods

No reproduction or republication permitted.