Bexarotene
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Bexarotene Definition
A synthetic retinoic acid agent with potential antineoplastic, chemopreventive, teratogenic and embryotoxic properties. Bexarotene selectively binds to and activates retinoid X receptors (RXRs), thereby inducing changes in gene expression that lead to cell differentiation, decreased cell proliferation, apoptosis of some cancer cell types, and tumor regression. (NCI04)
Bexarotene Synonyms
Bexarotene, 3-methyl TTNEB, 4-[1-(5,6,7,8-Tetrahydro-3,5,5,8,8-pentamethyl-2-naphthalenyl)ethenyl]benzoic Acid, BEXAROTENE, LGD1069, Targretin, bexarotene
Terms in Bexarotene category
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