Cancer Terms

Bisnafide Dimesylate

Cancer Terms -> Drugs and Chemicals -> Pharmacologic Substance -> Antineoplastic Agent -> DNA Binding Agent -> Intercalating Agent -> Bisnafide Dimesylate

Bisnafide Dimesylate Definition

The dimesylate salt form of bisnafide, a bis-naphthalimide compound with anticancer activity. Bisnafide selectively intercalates guanine-cytosine (GC) rich regions of DNA, thereby interfering with DNA replication machinery and activity of topoisomerase II. As a result, this agent causes potent cytotoxicity.

Bisnafide Dimesylate Synonyms

Bisnafide Dimesylate, BISNAFIDE DIMESYLATE

Terms in Bisnafide Dimesylate category



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