Cancer Terms

Bromfenac Sodium

Cancer Terms -> Drugs and Chemicals -> Pharmacologic Substance -> Agent Affecting Nervous System -> Analgesic Agent -> Nonnarcotic Analgesic -> Analgesic and Antipyretic -> Nonsteroidal Antiinflammatory Drug -> Bromfenac Sodium

Bromfenac Sodium Definition

The sodium salt form of bromfenac, a nonsteroidal anti-inflammatory drug (NSAID) with analgesic and anti-inflammatory activities. Upon ophthalmic administration, bromfenac binds to and inhibits the activity of cyclooxygenase II (COX II), an enzyme which converts arachidonic acid to cyclic endoperoxides, precursors of prostaglandins (PG). By inhibiting PG formation, bromfenac is able to inhibit PG-induced inflammation, thereby preventing vasodilation, leukocytosis, disruption of the blood-aqueous humor barrier, an increase in vascular permeability and an increase in intraocular pressure (IOP).

Bromfenac Sodium Synonyms

Bromfenac Sodium, BROMFENAC SODIUM

Terms in Bromfenac Sodium category



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