Cancer Terms

Bryostatin-1

Cancer Terms -> Drugs and Chemicals -> Pharmacologic Substance -> Enzyme Inhibitor -> Protein Kinase Inhibitor -> Protein Kinase C Inhibitor -> Bryostatin-1

Bryostatin-1 Definition

A macrocyclic lactone isolated from the bryozoan Bugula neritina with antineoplastic activity. Bryostatin 1 binds to and inhibits the cell-signaling enzyme protein kinase C, resulting in the inhibition of tumor cell proliferation, the promotion of tumor cell differentiation, and the induction of tumor cell apoptosis. This agent may act synergistically with other chemotherapeutic agents. (NCI04)

Bryostatin-1 Synonyms

Bryostatin 1, B705008K112, Bryostatin I, bryostatin 1

Terms in Bryostatin-1 category



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