Butyrylcholinesterase
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Butyrylcholinesterase Definition
Human butyrylcholinesterase protein (602 aa, 68 kD), a serine esterase, is encoded by the human butyrylcholinesterase (BCHE) gene. This protein, a homotetramer, is present in most cells (except erythrocytes) and catalyzes the hydrolysis of acylcholines to yield a choline and a carboxylate anion. Reduced serum activity of the BCHE protein causes hypocholinesterasemia, a condition resulting in sensitivity to the muscle relaxant suxamethonium, which is commonly used in association with surgical anesthesia.
Butyrylcholinesterase Synonyms
Butyrylcholinesterase, Acylcholine Acylhydrolase, BCHE, Butyrylcholine Esterase, CHE1, Choline Esterase II, Cholinesterase, Plasma Cholinesterase, Pseudocholinesterase, Pseudocholinesterase E1
Terms in Butyrylcholinesterase category
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