Cancer Terms

Butyrylcholinesterase

Cancer Terms -> Gene Product -> Protein -> Protein Organized by Function -> Enzyme -> Hydrolase -> Esterase -> Butyrylcholinesterase

Butyrylcholinesterase Definition

Human butyrylcholinesterase protein (602 aa, 68 kD), a serine esterase, is encoded by the human butyrylcholinesterase (BCHE) gene. This protein, a homotetramer, is present in most cells (except erythrocytes) and catalyzes the hydrolysis of acylcholines to yield a choline and a carboxylate anion. Reduced serum activity of the BCHE protein causes hypocholinesterasemia, a condition resulting in sensitivity to the muscle relaxant suxamethonium, which is commonly used in association with surgical anesthesia.

Butyrylcholinesterase Synonyms

Butyrylcholinesterase, Acylcholine Acylhydrolase, BCHE, Butyrylcholine Esterase, CHE1, Choline Esterase II, Cholinesterase, Plasma Cholinesterase, Pseudocholinesterase, Pseudocholinesterase E1

Terms in Butyrylcholinesterase category



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