CCNB2 wt Allele

Cancer Terms -> Gene -> Cell Cycle Gene -> Cyclin Gene -> CCNB2 Gene -> CCNB2 wt Allele

CCNB2 wt Allele Definition

Human CCNB2 wild-type allele is located in the vicinity of 15q22.2 and is approximately 20 kb in length. This allele, which encodes G2/mitotic-specific cyclin-B2 protein, is involved in the regulation of the mitotic G2/M transition of the cell cycle. Aberrant allelic expression, resulting from different mechanisms, could contribute through an alteration of the spindle checkpoint, to the chromosomal instability observed in cancer.

CCNB2 wt Allele Synonyms

CCNB2 wt Allele, Cyclin B2 wt Allele

Terms in CCNB2 wt Allele category

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