Cancer Terms

CCNE1 wt Allele

Cancer Terms -> Gene -> Cell Cycle Gene -> Cyclin Gene -> CCNE1 Gene -> CCNE1 wt Allele

CCNE1 wt Allele Definition

Human CCNE1 wild-type allele is located within 19q12 and is approximately 12 kb in length. This allele, which encodes G1/S-specific cyclin-E1 protein, is involved in the regulation of the G1/S transition of the cell cycle. Variant allelic overexpression has been observed in many tumors, which results in chromosome instability, and thus may contribute to tumorigenesis.

CCNE1 wt Allele Synonyms

CCNE1 wt Allele, CCNE, CGE1, Cyclin E1 wt Allele

Terms in CCNE1 wt Allele category



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