CD3D wt Allele

Cancer Terms -> Gene -> Protein Complex Subunit Gene -> CD3D Gene -> CD3D wt Allele

CD3D wt Allele Definition

Human CD3D wild-type allele is located within 11q23 and is approximately 4 kb in length. This allele, which encodes T-cell surface glycoprotein CD3 delta chain protein, plays a role in the regulation of signal transduction underlying the developmental transition of immature thymocytes to mature CD4+ or CD8+ T cells. Certain allelic variants of the CD3D gene cause a form of severe combined immunodeficiency (SCID) characterized by the absence of T cells but normal numbers of B cells and NK cells.

CD3D wt Allele Synonyms

CD3D wt Allele, CD3D Antigen, Delta Polypeptide (TiT3 Complex) wt Allele, T3D

CD3D wt Allele

CD3D wt Allele Definition

CD3D wt Allele Synonyms

Terms in CD3D wt Allele category