Cancer Terms

CDC7 Kinase Inhibitor BMS-863233

Cancer Terms -> Drugs and Chemicals -> Pharmacologic Substance -> Enzyme Inhibitor -> Protein Kinase Inhibitor -> Serine Threonine Kinase Inhibitor -> CDC7 Kinase Inhibitor BMS-863233

CDC7 Kinase Inhibitor BMS-863233 Definition

An orally bioavailable cell division cycle 7 homolog (CDC7) kinase inhibitor with potential antineoplastic activity. CDC7 kinase inhibitor BMS-863233 binds to and inhibits the activity of CDC7, which may result in the inhibition of DNA replication and mitosis, the induction of tumor cell apoptosis, and the inhibition of tumor cell proliferation in CDC7-overexpressing tumor cells. CDC7, a serine-threonine kinase overexpressed in a variety of tumor cell types, plays an essential role in the initiation of DNA replication by activating origins of replication.

CDC7 Kinase Inhibitor BMS-863233 Synonyms

CDC7 Kinase Inhibitor BMS-863233, BMS-863233, Cell Division Cycle 7 Homolog Kinase Inhibitor BMS-863233

Terms in CDC7 Kinase Inhibitor BMS-863233 category



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