Cancer Terms

CDKN2A wt Allele

Cancer Terms -> Gene -> Cell Cycle Gene -> Cyclin-Dependent Kinase Inhibitor Gene -> CDKN2A Gene -> CDKN2A wt Allele

CDKN2A wt Allele Definition

Human CDKN2A wild-type allele is located in the vicinity of 9p21 and is approximately 27 kb in length. This allele, which encodes cyclin-dependent kinase inhibitor 2A protein, isoforms 1/2/3, is involved in cell cycle regulation at the G1 phase. The allele is frequently mutated or deleted in a wide variety of tumors, and is known to be an important tumor suppressor gene.

CDKN2A wt Allele Synonyms

CDKN2A wt Allele, ARF, CDK4I, CDKN2, CDKN2 Gene, CMM2, Cyclin-Dependent Kinase Inhibitor 2A wt Allele, INK4, INK4A, MLM, MTS1, TP16, TSG9A, p14ARF, p16INK4a

Terms in CDKN2A wt Allele category



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