CISH wt Allele

Cancer Terms -> Gene -> Regulatory Gene -> Suppressor of Cytokine Signaling Family Gene -> CISH Gene -> CISH wt Allele

CISH wt Allele Definition

Human CISH wild-type allele is located in the vicinity of 3p21.3 and is approximately 5 kb in length. This allele, which encodes the cytokine inducible SH2-containing protein, is involved in the suppression of cytokine signaling. Deletion of the CISH wild-type allele may play a role in the pathogenesis of renal cell carcinomas and of lung cancer.

CISH wt Allele Synonyms

CISH wt Allele, CIS Gene, CIS-1 Gene, Cytokine-Inducible Inhibitor of Signaling Type 1B Gene, Cytokine-Inducible SH2-Containing Protein wt Allele, G18 Gene, SOCS Gene, Suppressor of Cytokine Signaling Gene

Terms in CISH wt Allele category

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