COMT wt Allele
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COMT wt Allele Definition
Human COMT wild-type allele is located in the vicinity of 22q11.21 and is approximately 27 kb in length. This allele, which encodes catechol O-methyltransferase protein, plays a role in the O-methylation-mediated inactivation of catecholamine neurotransmitters and catechol hormones. Defects in the COMT gene are associated with susceptibility to neurological disorders such as schizophrenia and bipolar disorder.
COMT wt Allele Synonyms
COMT wt Allele, Catechol-O-Methyltransferase wt Allele
Terms in COMT wt Allele category
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