CTLA4 wt Allele
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CTLA4 wt Allele Definition
Human CTLA4 wild-type allele is located within 2q33 and is approximately 6 kb in length. This allele, which encodes cytotoxic T-lymphocyte protein 4, is involved in signal transduction and T-cell regulation. Variant alleles generated from mutations in the gene, have been associated with insulin-dependent diabetes mellitus, Graves disease, Hashimoto thyroiditis, celiac disease, systemic lupus erythematosus, thyroid-associated orbitopathy, and other autoimmune diseases.
CTLA4 wt Allele Synonyms
CTLA4 wt Allele, CD152 Antigen Gene, CD152 Gene, CTLA-4 Gene, CTLA4, Cytotoxic T-Lymphocyte Protein 4 Gene, Cytotoxic T-Lymphocyte-Associated Antigen 4 Gene, Cytotoxic T-Lymphocyte-Associated Protein 4 wt Allele, Cytotoxic T-Lymphocyte-Associated Serine Esterase-4 Gene
Terms in CTLA4 wt Allele category
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