CYP1A2 1 Allele
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CYP1A2 Gene -> CYP1A2 1 Allele
CYP1A2 1 Allele Definition
Human CYP1A2*1 allele is located within 15q24 and is approximately 8 kb in length. This allele, a variant form of the CYP1A2 wild-type allele, encodes cytochrome P450 1A2*1 protein. There are multiple haplotypes of the CYP1A2*1 allele. Both CYP1A2*1C, which has a SNP (g.-3860G>A) in the 5' flanking region of the gene, and CYP1A2*1K, which has a SNP (g.-729C>T) in intron 1, encode cytochrome P450 1A2*1 proteins that exhibit decreased in vivo enzymatic activity. CYP1A2*1F exhibits a SNP (g.-163C>A) in intron 1 that has been linked with higher enzyme inducibility.
CYP1A2 1 Allele Synonyms
CYP1A2*1 Allele, CYP1A2*1, CYP1A2, g.-3860G>A, g.-729C>T, g.-163C>A, CYP1A2, wild-type, Cytochrome P450, Family 1, Subfamily A, Polypeptide 2*1 Allele
Terms in CYP1A2 1 Allele category
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